Report on the R&D of 25% pirimiphos-methyl SC small trial

1. Formulation difficulties and problems

25% pymetrozine SC, its pymetrozine original drug if the wet powder pymetrozine, the formulation is very simple, with ordinary polyether modifier with a little polycarboxylate can be done. However, most of the original drug of pyrithioxin on the market is dry powder original drug, the formulation is more difficult, there are the following difficulties: 1, the ingredients are sticky, grinding paste, and even the ingredients on the paste; 2, with ordinary acidic dispersant to do, although it can be easy to grind, but the thermal storage of precipitation of water is generally more; 3, the quality of the market of dry powder pyrithioxin is uneven, and the price is also a big difference between the additives, some additives have a good original drug to do, and some is not good to do, additives Selectivity of the original drug.

2. Formulation

3.Testing the preparation indexes

1.Preparation appearance white, hot storage for 14 days, precipitation 5%. Take the qualified sample to continue to refine the experiment, and measure the indicators.

2.Cold storage stability qualified.

3.ph=3.80, in a reasonable range and so on.

4.Preparation dilution stability.

Preparation standard hard water dilution 200 times placed 2h, suspension rate > 98%.

4.Summary

We experimented with almost all of the original drug on the market, from the experiments can be seen KY-SC125B in the pyraclostrobin suspension has a good application effect! We not only tested 25% pymetrozine SC, there are 24% pymetrozine + 12% spirotetramat, 20% pymetrozine + 10% KKSC, KY-SC125B not only can be applied to pymetrozine suspension single agent, but also can be applied to almost all the high content of pymetrozine compound suspension. ky-SC125B can be easily dealt with! Free samples are welcome.